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Mechanisms of arsenic trioxide induced apoptosis of human cervical cancer HeLa cells and protection by Bcl-2

✍ Scribed by Youping Deng; Chen Lin; Jie Zheng; Xiao Liang; Jieping Chen; Ming Fu; Peigen Xiao; Min Wu


Publisher
Science in China Press (SCP)
Year
1999
Tongue
English
Weight
732 KB
Volume
42
Category
Article
ISSN
1674-7305

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## Abstract Previously, we have shown that the release of AIF from mitochondria is required for As~2~O~3~‐induced cell death in human cervical cancer cells, and that reactive oxygen species (ROS) is necessary for AIF release from mitochondria. In this study, we further investigated the role of MAPK

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