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Mechanisms of apoptotic cell death

✍ Scribed by Rowan, S; Fisher, D E

Book ID: 110053478
Publisher: Nature Publishing Group
Year: 1997
Tongue: English
Weight: 131 KB
Volume: 11
Category: Article
ISSN: 0887-6924
DOI: 10.1038/sj.leu.2400626

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## Background: More than 95% of metastatic androgen independent prostatic cancer cells per day are in a proliferatively quiescent g0 state [berges et al.: clin cancer res 1:473-480, 1995] limiting their responsiveness to anti-proliferative chemotherapeutic agents. novel therapeutics capable of acti