Normal tissue function depends on adequate supply of oxygen through blood vessels. Understanding how blood vessels form has become a principal, yet challenging, objective of the last decade. Unraveling these mechanisms would offer therapeutic options to ameliorate or perhaps even cure disorders that
Mechanisms of angiogenesis and arteriogenesis
โ Scribed by Carmeliet, Peter
- Book ID
- 109828032
- Publisher
- Nature Publishing Group
- Year
- 2000
- Tongue
- English
- Weight
- 578 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1078-8956
- DOI
- 10.1038/74651
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## Abstract In this review, the concept of oxygen homeostasis will be presented as an organizing principle for discussion of the phylogeny, ontogeny, physiology, and pathology of blood vessel formation and remodeling, with a focus on molecular mechanisms and potential therapeutic applications. J. C
## Summary Different forms of vessel growth in the adult organism contribute to the compensation for an occluded artery. We here summarize the major differences between arteriogenesis and angiogenesis and provide evidence in favour of a therapeutic stimulation of collateral growth. In addition, we