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Mechanisms of amyloid fibril formation – focus on domain-swapping

✍ Scribed by Eva Žerovnik; Veronika Stoka; Andreja Mirtič; Gregor Gunčar; Jože Grdadolnik; Rosemary A. Staniforth; Dušan Turk; Vito Turk

Book ID
111313948
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
481 KB
Volume
278
Category
Article
ISSN
1432-1327

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## Abstract Caspase‐activated DNase (CAD) is a key protein in the process of apoptosis that degrades DNA through the action of caspases. Its N‐terminal region, the CAD domain (CAD‐CD), is highly conserved among CAD family proteins and is responsible for the interaction with its inhibitor. We report