Mechanisms of Action Involved in Ozone Therapy: Is healing induced via a mild oxidative stress?

PAK2 is cleaved and activated during hyp

PAK2 is cleaved and activated during hyperosmotic shock-induced apoptosis via a caspase-dependent mechanism: Evidence for the involvement of oxidative stress

✍ Wen-Hsiung Chan; Jau-Song Yu; Shiaw-Der Yang 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 364 KB 👁 2 views

Hyperosmotic shock elicits a stress response in mammalian cells and can lead to apoptotic cell death. In the present study, we report that hyperosmotic shock can induce activation of a 36 kDa kinase detected by an in-gel kinase assay in several cell types, including mouse Balb/c 3T3 fibroblasts, and