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Mechanisms of 4-hydroxytamoxifen anti-growth factor activity in breast cancer cells: Alterations of growth factor receptor binding sites and tyrosine kinase activity

✍ Scribed by Gilles Freiss; Henri Rochefort; Françoise Vignon


Book ID
117055140
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
622 KB
Volume
173
Category
Article
ISSN
0006-291X

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## Abstract Angiotensin II (Ang II) induces, through AT1, intracellular Ca^2+^ increase in both normal and cancerous breast cells in primary culture (Greco et al., 2002 Cell Calcium 2:1–10). We here show that Ang II stimulated, in a dose‐dependent manner, the 24 h‐proliferation of breast cancer cel