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Mechanisms influencing the vasoactive effects of lidocaine in human skin

✍ Scribed by D. J. Newton; G. A. McLeod; F. Khan; J. J. F. Belch

Book ID
108628416
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
491 KB
Volume
62
Category
Article
ISSN
0003-2409

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✍ D. J. Newton; E. L. Sur; F. Khan; G. A. McLeod; J. J. F. Belch πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 147 KB

**Summary** We investigated the roles of the endothelial nitric oxide and cyclo‐oxygenase pathways in mediating the vasoactivity of prilocaine in the skin. We injected prilocaine 1% intradermally into forearm skin of 10 healthy, male subjects. Nitric oxide synthesis was inhibited at a second site by