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Mechanisms in cyclophosphamide induction of cytogenetic damage in human lymphocyte cultures

✍ Scribed by Linda M. Sargent; Boyd Roloff; Lorraine F. Meisner

Book ID
119103601
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
243 KB
Volume
29
Category
Article
ISSN
0165-4608

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Some chemotherapeutic approaches have proposed the use of antioxidants such as vitamin C (VC) to minimize the cytotoxicity and damage induced in normal tissue by antitumor agents that produce free radicals. Nevertheless, VC can also be cytotoxic, genotoxic, and harmful when combined with antitumor a