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Mechanisms for the selective action of Vitamin D analogs

✍ Scribed by Roger Bouillon; Lieve Verlinden; Guy Eelen; Pierre De Clercq; Maurits Vandewalle; Chantal Mathieu; Annemieke Verstuyf

Book ID
116697670
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
251 KB
Volume
97
Category
Article
ISSN
0960-0760

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## Abstract The biologically active metabolite of vitamin D, 1,25‐dihydroxyvitamin D~3~ (1,25(OH)~2~D~3~) is a secosteroid whose genomic mechanism of action is similar to that of other steroid hormones and is mediated by stereospecific interaction of 1,25(OH)~2~D~3~ with the vitamin D receptor (VDR