Human embryonic stem cells (hESCs), derived from the inner cell mass (ICM) of the blastocyst, have the capacity for longterm undifferentiated growth in culture and the theoretical potential to differentiate into all somatic cell types. [1] These hESCs offer not only a model system for human developm
Mechanisms and factors in embryonic stem cell self-renewal
β Scribed by Ian Chambers
- Publisher
- Springer Milan
- Year
- 2005
- Weight
- 283 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1120-6349
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Human embryonic stem cells (hESCs), derived from the inner cell mass (ICM) of the blastocyst, have the capacity for longterm undifferentiated growth in culture and the theoretical potential to differentiate into all somatic cell types. [1] These hESCs offer not only a model system for human developm
## Abstract Embryonic stem cells (ES cells) are derived from inner cell mass (ICM). The selfβrenewal and pluripotency are the main specificities of ES cells, which are likely to reveal a deeper understanding of human cellular biology and which are considered to be promising sources for cell therapy
## Abstract Stem cells have two common properties: the capacity for selfβrenewal and the potential to differentiate into one or more specialized cell types. In general, stem cells can be divided into two broad categories: adult (somatic) stem cells and embryonic stem cells. Recent evidence suggeste