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Mechanisms and attenuation of hemostatic activation during extracorporeal circulation

โœ Scribed by George J. Despotis; Michael S. Avidan; Charles W. Hogue Jr

Book ID
117034123
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
234 KB
Volume
72
Category
Article
ISSN
0003-4975

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โœ Terry C. Major; David O. Brant; Melissa M. Reynolds; Robert H. Bartlett; Mark E. ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 938 KB

Nitric oxide (NO) has been shown to reduce thrombogenicity by decreasing platelet and monocyte activation by the surface glycoprotein, P-selectin and the integrin, CD11b, respectively. In order to prevent platelet and monocyte activation with exposure to an extracorporeal circulation (ECC), a nitric