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Mechanism of vitamin D action and its regulation

✍ Scribed by AS Dusso; AJ Brown

Book ID
117814561
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
167 KB
Volume
32
Category
Article
ISSN
0272-6386

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We and others have previously shown that selected vitamin D analogs potentiate the vitamin D receptor (VDR) mediated transcription much more efficiently than the natural hormone itself. Here we show that the transcriptionally active 20-epi analogs, namely KH 1060 and MC 1288, protect VDR against deg