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Mechanism of the defect in gap-junctional communication by expression of a connexin 26 mutant associated with dominant deafness

โœ Scribed by Chen, Y.


Book ID
120042314
Publisher
The Federation of American Societies for Experimental Biology
Year
2005
Tongue
English
Weight
123 KB
Volume
19
Category
Article
ISSN
0892-6638

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The tumor-suppressive property of the connexin gap-junction proteins was postulated from the fact that their function of cell coupling is impaired in most cancer cells. However, in conflict with this notion, certain cancer cells are able to communicate through gap junctions despite their malignancy.