Mechanism of the carbodiimide reaction. II. Peptide synthesis on the solid phase
โ Scribed by Rebek, Julius; Feitler, David
- Book ID
- 121290954
- Publisher
- American Chemical Society
- Year
- 1974
- Tongue
- English
- Weight
- 233 KB
- Volume
- 96
- Category
- Article
- ISSN
- 0002-7863
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๐ SIMILAR VOLUMES
A rapid and sensitive method for the quantitative determination of free amino groups during solid-phase peptide synthesis has been developed. The technique involves the reaction of the free amine with ninhydin under carefully controlled conditions and the determination of the resulting chromophore i
In one of the peptide condensation methods termed thioester method, an amino protecting group is required in the lysine side chain. In this study, to investigate the efficiency of the pyruvoyl group as an amino protecting group, we synthesized N a -fluorenylmethoxycarbonyl (Fmoc)-N e -pyruvoyl-lysin