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Mechanism of target cell lysis by cytolytic T lymphocytes. Characterization of specific lymphocyte-target cell conjugates separated by velocity sedimentation

✍ Scribed by J.-C. Cerottini; J.-E. Ryser; B. Sordat; K. T. Brunner


Publisher
John Wiley and Sons
Year
1977
Tongue
English
Weight
904 KB
Volume
7
Category
Article
ISSN
0014-2980

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✍ Bruno Robert; Philippe Guillaume; Immanuel Luescher; Pedro Romero; Jean-Pierre M πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 114 KB πŸ‘ 1 views

To demonstrate that antibody-guided targeting of antigenic MHC class I-peptide tetramer on tumor cells can render them susceptible to lysis by relevant cytotoxic T lymphocytes (CTL), biotinylated HLA-A\*0201/Flu matrix peptide complexes were tetramerized on streptavidin molecules previously coupled