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Mechanism of stereoselective interaction between butyrylcholinesterase and ethopropazine enantiomers

✍ Scribed by Goran Šinko; Zrinka Kovarik; Elsa Reiner; Vera Simeon-Rudolf; Jure Stojan


Book ID
116309435
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
999 KB
Volume
93
Category
Article
ISSN
0300-9084

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5-Dimethylsulfamoyl-6,7-dichloro-2,3-dihydrobenzofuran-2-carboxyli c acid (DBCA), a promising uricosuric, diuretic, and antihypertensive agent, was administered intravenously to rats. The levels of DBCA in plasma and the areas under the curve of concentration versus time (AUC values) of the S(-)-ena