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Mechanism of resistance to U-90152S and sensitization to L-697,661 by a proline to leucine change at residue 236 of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase

✍ Scribed by Naisheng Fan; David B. Evans; Kenneth B. Rank; Richard C. Thomas; W.Gary Tarpley; Satish K. Sharma

Book ID: 115930457
Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 631 KB
Volume: 359
Category: Article
ISSN: 0014-5793
DOI: 10.1016/0014-5793(95)00051-a

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55 Selection of human immunodeficiency v

55 Selection of human immunodeficiency virus type 1 (Hiv-1) resistant to the nucleoside inhibitor 2′,3′-dideoxy-5-fluoro-3′-thiacytidine (Ftc) in cell culture due to a single mutation in the reverse transcriptase: M. Tisdale, N. R. Parry, S. D. Kemp and B. A. Larder, Department of Molecular Sciences, The Wellcome Research Laboratories, Beckenham, Kent BR3 3BS, U.K.

📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 65 KB