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Mechanism of reactions of unsaturated ethers and thioethers. VII: Linear free energy relationships and inverse secondary deuterium isotope effect in the addition of water to 1-alkynyl thioethers

✍ Scribed by H. Hogeveen; W. Drenth


Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
410 KB
Volume
82
Category
Article
ISSN
0165-0513

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📜 SIMILAR VOLUMES


Mechanism of reactions of unsaturated et
✍ H. Hogeveen; W. Drenth 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 767 KB

## Abstract Infrared analysis has shown that acid‐catalyzed hydration of ethylthioethyne in heavy water does not involve the uptake of deuterium in the initial compound. This confirms earlier evidence that protonation of the triple bond is the rate‐determining step. Values for the entropy of activ

Mechanism of reactions of unsaturated et
✍ E. J. Stamhuis; W. Drenth 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 360 KB

## Abstract Additional evidence for the occurrence of a rate determining proton transfer in the hydration of 1‐alkynyl ethers is afforded by the value of the solvent deuterium isotope effect, k/k = 1.7. The addition of water to 1‐ethoxy‐1‐propyne was investigated in a series of alcohol‐water mixtu