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Mechanism of proteoglycan aggregate degradation in cartilage stimulated with oncostatin M

✍ Scribed by M. Durigova; P.J. Roughley; J.S. Mort


Book ID
113732648
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
574 KB
Volume
16
Category
Article
ISSN
1063-4584

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Objective. To investigate the effects of the interleukind (IL-6) family cytokines, such as IL-6, IL-11, leukemia inhibitory factor (LIF), and oncostatin M (OSM), on the production of tissue inhibitor of matrix metalloproteinases 1 (TIMP-1) in human articular cartilage. Methods. Effects of IL-6 fami