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Mechanism of prostaglandin biosynthesis. I. Characterization and assay of bovine prostaglandin synthetase

โœ Scribed by Sih, Charles J.; Takeguchi, C.; Kohno, E.


Book ID
126971931
Publisher
American Chemical Society
Year
1971
Tongue
English
Weight
491 KB
Volume
10
Category
Article
ISSN
0006-2960

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Purification of prostaglandin H syntheta
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Prostaglandin H synthetase (PGH synthetase) has been purified to homogeneity from sheep vesicular glands. The pure enzyme has a specific activity of about 40 @.I of arachidonic acid consumed per minute per milligram of protein, which corresponds to a turnover number of 2800 mitt-' per subunit. The p