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Mechanism of NH proton exchange in amides and proteins: solvent effects and solvent accessibility

โœ Scribed by Perrin, Charles L.; Lollo, Charles Peter


Book ID
120211585
Publisher
American Chemical Society
Year
1984
Tongue
English
Weight
580 KB
Volume
106
Category
Article
ISSN
0002-7863

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We examined the variation in the solvent accessibility and hydrophobicity of the amino acids along the sequences of 58 soluble globular proteins with known tertiary structure. We found that there is a significant tendency for the accessibilities to run in clusters along the sequence but that the hyd