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Mechanism of methylmercury efflux from cultured astrocytes

✍ Scribed by Jiro Fujiyama; Kimiko Hirayama; Akira Yasutake


Book ID
115784128
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
586 KB
Volume
47
Category
Article
ISSN
0006-2952

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High concentrations of thrombin (Thr) have been linked to neuronal damage in cerebral ischemia and traumatic brain injury. In the present study we found that Thr markedly enhanced swelling-activated efflux of (3)H-glutamate from cultured astrocytes exposed to hyposmotic medium. Thr (0.5-5 U/mL) elic