Mechanism of lapatinib-mediated radiosensitization of breast cancer cells is primarily by inhibition of the Raf > MEK > ERK mitogen-activated protein kinase cascade and radiosensitization of lapatinib-resistant cells restored by direct inhibition of MEK

✍ Scribed by Maria J. Sambade; J. Terese Camp; Randall J. Kimple; Carolyn I. Sartor; Janiel M. Shields

• Book ID: 118497532
• Publisher: Elsevier Science
• Year: 2009
• Tongue: English
• Weight: 448 KB
• Volume: 93
• Category: Article
• ISSN: 0167-8140
• DOI: 10.1016/j.radonc.2009.09.006