Mechanism of Graded Persistent Cellular Activity of Entorhinal Cortex Layer V Neurons
✍ Scribed by Erik Fransén; Babak Tahvildari; Alexei V. Egorov; Michael E. Hasselmo; Angel A. Alonso
- Book ID
- 116782601
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 474 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0896-6273
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This study aimed to characterize the morphological and electrophysiological properties of neurons in layer V of the entorhinal cortex in the rat brain. Using the in vitro slice preparation and sharp electrode techniques, we recorded from layer V neurons located in the medial entorhinal cortex. Recor
## Abstract Persistent neural spiking maintains information during a working memory task when a stimulus is no longer present. During retention, this activity needs to be stable to distractors. More importantly, when retention is no longer relevant, cessation of the activity is necessary to enable