Mechanism of gel permeation chromatography: distribution coefficient

✍ Scribed by M.E. Van Kreveld; N. Van Den Hoed

• Publisher: Elsevier Science
• Year: 1973
• Tongue: English
• Weight: 979 KB
• Volume: 83
• Category: Article
• ISSN: 1873-3778
• DOI: 10.1016/s0021-9673(00)97032-8

✦ Synopsis

In a study of the separation mechanism of gel permeation chromatography, we have represented the porous material by a structure built up from randomly distributed identical spheres and the macromolecules by random coils. The relationship derived between molecular weight and accessible pore volume is in excellent agreement with the experimental results.