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Mechanism of galanin-inhibited insulin release : Occurrence of a pertussis-toxin-sensitive inhibition of adenylate cyclase

✍ Scribed by Brigitte AMIRANOFF; Anne-Marie LORINET; Isabelle LAGNY-POURMIR; Marc LABURTHE


Book ID
115125995
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
707 KB
Volume
177
Category
Article
ISSN
1432-1327

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✍ B. Ewa Snaar-Jagalska; Peter J. M. Haastert πŸ“‚ Article πŸ“… 1990 πŸ› Springer 🌐 English βš– 958 KB

cAMP binds to surface receptors of Dictyostelium discoideum cells, transducing the signal to adenylate cyclase, guanylate cyclase and to chemotaxis. The activation of adenylate cyclase is maximal after 1 min and then declines to basal levels due to desensitization, which is composed to two component