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Mechanism of dissociation of S-peptide from ribonuclease S

โœ Scribed by Schreier, Alan A.; Baldwin, Robert L.


Book ID
126230850
Publisher
American Chemical Society
Year
1977
Tongue
English
Weight
862 KB
Volume
16
Category
Article
ISSN
0006-2960

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Stabilization of the ribonuclease S-pept
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The effects of trifluoroethanol (TFE) on the stability of the alpha-helix formed by ribonuclease S-peptide, residues 1-19 of ribonuclease A, were studied by measuring circular dichroism as a function of TFE concentration, pH, and temperature. The S-peptide forms an unusually stable alpha-helix, whic