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Mechanism of Cytotoxicity and Cellular Uptake of Lipophilic Inert Dinuclear Polypyridylruthenium(II) Complexes

✍ Scribed by Michelle J. Pisani; Phillip D. Fromm; Dr. Yanyan Mulyana; Dr. Ronald J. Clarke; Prof. Heinrich Körner; Prof. Kirsten Heimann; Prof. J. Grant Collins; Prof. F. Richard Keene

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
574 KB
Volume
6
Category
Article
ISSN
1860-7179

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## Abstract Various possible pathways for the uptake of cationic alkylamine platinum(II) complexes into the MCF‐7 breast cancer cells were studied with di[meso‐1,2‐bis(4‐fluorophenyl)ethylenediamine]di[sulfinylbis(methane)‐S][μ‐1,6‐diaminohexaneN:N′]diplatinum(II) disulfate (m‐4F‐PtDMSO‐DAH) as an