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Mechanism of cyanogen bromide reaction with methionine in peptides and proteins: I. Formation of imidate and methyl thiocyanate

โœ Scribed by A.S. Inglis; P. Edman


Publisher
Elsevier Science
Year
1970
Tongue
English
Weight
402 KB
Volume
37
Category
Article
ISSN
0003-2697

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Reaction mechanisms in peptide synthesis
โœ Jerzy Ciarkowski; Francis M. F. Chen; N. Leo Benoiton ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Springer Netherlands ๐ŸŒ English โš– 712 KB

2,4-Dialkyl-5(4H)-oxazolones are well-recognized intermediates in some aminolysis reactions in peptide synthesis. Using the MOPAC molecular orbital programs, detailed geometric and energetic characteristics of the elementary reaction pathways for the additions of water and ammonia to 2-methyl-5(4H)-