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Mechanism of cell death induced by cis-3, 4′, 5-trimethoxy-3′-aminostilbene in ovarian cancer

✍ Scribed by David Durrant; Joanna E. Richards; Winston T. Walker; Kristen A. Baker; Daniele Simoni; Ray M. Lee

Book ID: 113961563
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 844 KB
Volume: 110
Category: Article
ISSN: 0090-8258
DOI: 10.1016/j.ygyno.2008.02.031

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## Abstract Signal transducer and activator of transcription 3 (STAT3) is activated in a variety of human cancers, including ovarian cancer. The molecular mechanism by which the STAT3 is activated in cancer cells is poorly understood. We observed that human ovarian xenograft tumors (A2780) in mice