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Mechanism of carcinogenesis induced by a veterinary antimicrobial drug, nitrofurazone, via oxidative DNA damage and cell proliferation

โœ Scribed by Yusuke Hiraku; Aki Sekine; Hiromi Nabeshi; Kaoru Midorikawa; Mariko Murata; Yoshito Kumagai; Shosuke Kawanishi


Book ID
116333193
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
247 KB
Volume
215
Category
Article
ISSN
0304-3835

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## Abstract Epidemiological and animal model studies have suggested that high intake of heme, present in red meat, is associated with an increased risk of colon cancer. However, the mechanisms underlying this association are not clear. This study aimed to investigate whether heme induces DNA damage