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Mechanism of action of cobalt ions on rat osseous plate alkaline phosphatase

✍ Scribed by Pietro Ciancaglini; João Martins Pizauro; Francisco Assis Leone

Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
606 KB
Volume
60
Category
Article
ISSN
0162-0134

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📜 SIMILAR VOLUMES

Rat osseous plate alkaline phosphatase:
Rat osseous plate alkaline phosphatase: mechanism of action of manganese ions
✍ F. A. Leone; P. Ciancaglini; J. M. Pizauro; A. A. Rezende 📂 Article 📅 1995 🏛 Springer Netherlands 🌐 English ⚖ 385 KB

Polidocanol-solubilized osseous plate alkaline phosphatase was modulated by manganese ions in a similar way as by zinc ions. For concentrations up to 1.0 nM, the enzyme was stimulated by manganese ions, showing site-site interactions (n = 2.2). However, larger concentrations (> 0.1/w) were inhibitor