๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Mechanism of Action and Structural Requirements of Constrained Peptide Inhibitors of RGS Proteins

โœ Scribed by Rebecca A. Roof; Yafei Jin; David L. Roman; Roger K. Sunahara; Masaru Ishii; Henry I. Mosberg; Richard R. Neubig

Book ID
111368288
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
365 KB
Volume
67
Category
Article
ISSN
1747-0277

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Mechanisms of action of peptide inhibito
Mechanisms of action of peptide inhibitors of mammalian ribonucleotide reductase targeting quaternary structure
โœ Ying Gao; Ossama B. Kashlan; Jaskiran Kaur; Chiheng Tan; Barry S. Cooperman ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 203 KB

Mammalian ribonucleotide reductase (mRR) is a chemotherapeutic target. The enzyme is composed of 2 subunits (mR1 and mR2) and is inhibited by Ac-FTLDADF (denoted P7), corresponding to the C-terminus of mR2, which competes with mR2 for binding to mR1. mRR has 2 physiologically important active forms,