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Mechanism and Specificity of an Acyltransferase Domain from a Modular Polyketide Synthase

✍ Scribed by Dunn, Briana J.; Cane, David E.; Khosla, Chaitan

Book ID
120347712
Publisher
American Chemical Society
Year
2013
Tongue
English
Weight
588 KB
Volume
52
Category
Article
ISSN
0006-2960

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## Background: Polyketides are important compounds with antibiotic and anticancer activities. several modular polyketide synthases (pkss) contain a terminal thioesterase (te) domain probably responsible for the release and concomitant cyclization of the fully processed polyketide chain. because the