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Mechanism and impact of allosteric AMPA receptor modulation by the AmpakineTM CX546

✍ Scribed by Naveen Nagarajan; Christoph Quast; Andrew R. Boxall; Mohammed Shahid; Christian Rosenmund


Book ID
117187250
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
371 KB
Volume
41
Category
Article
ISSN
0028-3908

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The synaptic modifications underlying long-term potentiation (LTP) and long-term depression (LTD) of synaptic transmission in various brain structures may result from changes in the properties of the ␣-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) subtype of glutamate receptors. In the pres