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Mechanically unfolding proteins: The effect of unfolding history and the supramolecular scaffold

✍ Scribed by Rebecca C. Zinober; David J. Brockwell; Godfrey S. Beddard; Anthony W. Blake; Peter D. Olmsted; Sheena E. Radford; D. Alastair Smith


Book ID
119982972
Publisher
Cold Spring Harbor Laboratory Press
Year
2009
Tongue
English
Weight
112 KB
Volume
11
Category
Article
ISSN
0961-8368

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## Abstract New experimental results show that either gain or loss of close packing can be observed as a discrete step in protein folding or unfolding reactions. This finding poses a significant challenge to the conventional two‐state model of protein folding. Results of interest involve dry molten