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Mechanical stimulation alters pleiotrophin expression of IVD cells and influences endothelial cell migration by conditioned media

✍ Scribed by C. Neidlinger-Wilke; K. Würtz; A. Liedert; J. Klasen; A. Ignatius; L. Claes; W.E.B. Johnson; S. Roberts


Book ID
108333227
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
161 KB
Volume
39
Category
Article
ISSN
0021-9290

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## Abstract Pleiotrophin (PTN) is a secreted growth factor involved in angiogenesis and tumor growth. We have recently shown that low concentrations of hydrogen peroxide (HP) stimulate PTN expression, through activation of the transcription factor AP‐1. In the present work, we studied the possible