Mechanical regulation of the Cyr61/CCN1 and CTGF/CCN2 proteins : Implications in mechanical stress-associated pathologies

CYR61 (CCN1) Protein Expression during F

CYR61 (CCN1) Protein Expression during Fracture Healing in an Ovine Tibial Model and Its Relation to the Mechanical Fixation Stability

✍ Jasmin Lienau; Hanna Schell; Devakara R. Epari; Norbert Schütze; Franz Jakob; Ge 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 413 KB

## Abstract The formation of new blood vessels is a prerequisite for bone healing. CYR61 (CCN1), an extracellular matrix‐associated signaling protein, is a potent stimulator of angiogenesis and mesenchymal stem cell expansion and differentiation. A recent study showed that CYR61 is expressed during