Mechanical model of neural tissue displacement during Lorentz effect imaging
✍ Scribed by Bradley J. Roth; Peter J. Basser
- Book ID
- 102534883
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 168 KB
- Volume
- 61
- Category
- Article
- ISSN
- 0740-3194
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✦ Synopsis
Abstract
Allen Song and coworkers recently proposed a method for MRI detection of biocurrents in nerves called “Lorentz effect imaging.” When exposed to a magnetic field, neural currents are subjected to a Lorentz force that moves the nerve. If the displacement is large enough, an artifact is predicted in the MR signal. In this work, the displacement of a nerve of radius a in a surrounding tissue of radius b and shear modulus μ is analyzed. The nerve carries a current density J and lies in a magnetic field B. The solution to the resulting elasticity problem indicates that the nerve moves a distance
$BJ/4|gm$a^2^ln($b/a$). Using realistic parameters for a human median nerve in a 4T field, this calculated displacement is 0.013 μm or less. The distribution of displacement is widespread throughout the tissue, and is not localized near the nerve. This displacement is orders of magnitude too small to be detected by conventional MRI methods. Magn Reson Med 61:59–64, 2009. © 2008 Wiley‐Liss, Inc.