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Mechanical load increases gene expression of Pdgf Receptor alpha and beta in Bladder smooth muscle cells

✍ Scribed by Maximilian Stehr; Martin Mucke; Cornelia Hasel; Hans-georg Dietz; Roland Kappler

Book ID: 118479903
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 36 KB
Volume: 4
Category: Article
ISSN: 1477-5131
DOI: 10.1016/j.jpurol.2008.01.019

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## Abstract Mechanical forces are well known to modulate smooth muscle cell growth and synthetic phenotype. The signals controlling this process are complex and potentially involve changes in the expression of peptide growth factor genes such as those of the insulin‐like growth factor (IGF) system.