Mechanical left ventricular unloading prior to reperfusion reduces infarct size in a canine infarction model

Left ventricular unloading with intra-ao

Left ventricular unloading with intra-aortic counter pulsation prior to reperfusion reduces myocardial release of endothelin-1 and decreases infarction size in a porcine ischemia-reperfusion model

✍ John F. LeDoux; Sophie Tamareille; Patty R. Felli; James Amirian; Richard W. Sma 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 292 KB

## Abstract ## Objectives: We tested the hypothesis that unloading the left ventricle with intra‐aortic balloon counter‐pulsation just prior to reperfusion provides infarct salvage compared with left ventricular (LV) unloading postreperfusion or reperfusion alone. ## Background: Previous reports