Mechanical and biologic link between cartilage and subchondral bone in osteoarthritis
โ Scribed by Li-Zhi Zhang; Hong-Ai Zheng; Yao Jiang; Yi-Hui Tu; Pei-Hong Jiang; An-Li Yang
- Book ID
- 111991816
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2012
- Tongue
- English
- Weight
- 132 KB
- Volume
- 64
- Category
- Article
- ISSN
- 2151-464X
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The zone of calcified cartilage (ZCC) forms an important interface between cartilage and bone for transmitting force, attaching cartilage to bone, and limiting diffusion from bone to the deeper layers of cartilage. The height of the ZCC is a relatively constant percent of articular cartilage and the
## Abstract Subchondral bone and articular cartilage play complementary roles in load bearing of the joints. Although the biomechanical coupling between subchondral bone and articular cartilage is well established, it remains unclear whether direct biochemical communication exists between them. Pre