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Mecamylamine increases nicotine preference and attenuates nicotine discrimination

โœ Scribed by J.E. Rose; A. Sampson; E.D. Levin; J.E. Henningfield

Book ID
113223121
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
560 KB
Volume
32
Category
Article
ISSN
0091-3057

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Mecamylamine pretreatment increases subs
Mecamylamine pretreatment increases subsequent nicotine self-administration as indicated by changes in plasma nicotine level
โœ C. S. Pomerleau; O. F. Pomerleau; M. J. Majchrzak ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› Springer ๐ŸŒ English โš– 326 KB

Acute administration of mecamylamine, a centrally active nicotinic cholinergic agonist, has been shown to increase amount of smoking as indicated by smoking topography (e.g., puff rate, puff duration), expired carbon monoxide changes, and other inferential measures. In the present study, subjects sh