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Measuring the peptides in individual organelles with mass spectrometry

✍ Scribed by Rubakhin, Stanislav S.; Garden, Rebecca W.; Fuller, Robert R.; Sweedler, Jonathan V.

Book ID
109827615
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
431 KB
Volume
18
Category
Article
ISSN
1087-0156

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Two model peptides, melittin and a growth hormone releasing factor (GRF) analog, have been studied by mass spectrometry and tandem mass spectrometry during the course of their deuterium exchange. Both peptides are known from previous work to form Ξ±-helices in solution. When the peptides are exposed