Measuring serum markers once or twice in each assay in antenatal screening for Down syndrome and neural tube defects

Alternative methods of maternal weight a

Alternative methods of maternal weight adjustment in maternal serum screening for Down syndrome and neural tube defects

✍ H. C. Watt; N. J. Wald 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 133 KB 👁 2 views

Serum markers used in screening for Down syndrome and neural tube defects are often adjusted to take account of the effect of maternal weight on the marker levels. The standard adjustment procedure is based on a linear relationship between the marker concentration, expressed as the log of the multip