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Measuring hepatitis C viremia in clinical samples: Can we trust the assays?

✍ Scribed by J Pawlotsky

Book ID: 102244048
Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 114 KB
Volume: 26
Category: Article
ISSN: 0270-9139
DOI: 10.1002/hep.510260131

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✦ Synopsis

HEPATOLOGY Concise Review onstrate HCV replication and to assess HCV clearance during

Measuring Hepatitis C Viremia and after therapy; 2) pretreatment HCV RNA thresholds predicting the various categories of response to antiviral treat-in Clinical Samples: Can We ments, 1,2 which can be used to tailor therapy to the level of HCV replication; and 3) RNA levels with prognostic value SENSITIVITY Abbreviations: HCV, hepatitis C virus; RT-PCR, reverse-transcriptase polymerase chain reaction; bDNA, branched DNA; CV, coefficient of variation. The performance of the bDNA assay version 2.0 and the From the Department of Bacteriology and Virology, Ho ˆpital Henri Mondor, Uni-Monitor assay can be interpreted in different ways acversite ´Paris XII, Cre ´teil, France.

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