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Measuring Dynamic Flexibility of the Coil State of a Helix-forming Peptide

✍ Scribed by Lisa J. Lapidus; William A. Eaton; James Hofrichter


Book ID
117142705
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
219 KB
Volume
319
Category
Article
ISSN
0022-2836

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Enthalpy distribution for the Ξ±-helix/ra
✍ Douglas Poland πŸ“‚ Article πŸ“… 2001 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 105 KB πŸ‘ 1 views

We use heat capacity data of Taylor et al. to calculate the enthalpy distribution of a model peptide using the moments/maximum-entropy method. The peptide was designed with small covalent loops at both ends of the molecule to nucleate ␣-helix thus giving a system that would be expected to show a hel