Measuring and increasing protein solubil
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Saul R. Trevino; J. Martin Scholtz; C. Nick Pace
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Article
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2008
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John Wiley and Sons
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English
β 211 KB
High concentration protein delivery is difficult to achieve for several protein pharmaceuticals due to low solubility. In this review, we discuss different types of low protein solubility, including low in vitro solubility, which is relevant to the formulation of protein pharmaceuticals. We also dis