Measurement of water motion (apparent diffusion) in biological systems

✍ Scribed by Neil, Jeffrey J.

• Publisher: John Wiley and Sons
• Year: 1997
• Tongue: English
• Weight: 243 KB
• Volume: 9
• Category: Article
• ISSN: 1043-7347
• DOI: 10.1002/(sici)1099-0534(1997)9:6<385::aid-cmr2>3.0.co;2-v

✦ Synopsis

This work describes the basics of diffusion measurement in biological systems. The first portion is dedicated to providing an understandable, classical-mechanical description of the Stejskal ᎐ Tanner pulse sequence to give the reader an intuitive understanding of the measurement. This is followed by a description of the various aspects of water motion in biological systems that should be taken into account when making and ( ) interpreting apparent diffusion coefficient ADC measurements. These include free diffusion, restricted diffusion, diffusion anisotropy, population weighting, and the difference ( ) between diffusion-weighted imaging DWI and ADC maps.