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Measurement of valproic acid in serum as the 4-bromophenacyl ester by high performance liquid chromatography

โœ Scribed by John P. Moody; Stella M. Allan


Book ID
117075397
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
335 KB
Volume
127
Category
Article
ISSN
0009-8981

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The use of 4'-bromo-2-hydroxyacetophenone trifluoromethanesulfonate ester (4'-bromophenacyl triflate) in the preparation of carboxylic acid 4'-bromophenacyl ester derivatives for spectrophotometric detection in high-performance liquid chromatography is described. The reagent is prepared in 66% yield